Rehabilitation and Neural Engineering Laboratory



Urbin M, Collinger J, and Wittenberg G. Corticospinal recruitment of spinal motor neurons in human stroke survivors. The Journal of Physiology. 2021 May 22;

Flesher S, Downey J, Weiss J, Hughes C, Herrera A, Tyler-Kabara E, Boninger M, Collinger J, Gaunt R. A brain-computer interface that evokes tactile sensations improves robotic arm control. Science. 2021 May 21;372(6544):831-836. doi: 10.1126/science.abd0380. PDF

Greiner N, Barra B, Schiavone G, Lorach H, James N, Cont, S, Kaeser M, Fallegger F, Borgognon S, Lacour S, Bloch J, Courtine G, Capogrosso M. Recruitment of Upper-Limb Motoneurons with Epidural Electrical Stimulation of the Cervical Spinal Cord. Nature Communications; 12, 435 (2021). DOI: 10.1038/s41467-020-20703-1


Mirzakhalili E, Barra B, Capogrosso M, Lempka SF. Biophysics of Temporal Interference Stimulation. Science Direct, 2020 Nov 5; DOI: 10.1016/j.cels.2020.10.004

Chandrasekaran S, Nanivadekar AC, McKernan G, Helm ER, Boninger ML, Collinger JL, Gaunt RA, Fisher LE. Sensory restoration by epidural stimulation of the lateral spinal cord in upper-limb amputees. eLife Sciences.  2020;9:e54349. DOI: 10.7554/eLife.54349.

Kolarcik CL, Castro CA, Lesniak A, Demetris AJ, Fisher LE, Gaunt RA, Weber DJ, Cui XT. Host tissue response to floating microelectrode arrays chronically implanted in the feline spinal nerve. Journal of Neural Engineering. 2020. DOI: 10.1088/1741-2552/ab94d7

Kibleur P, Tata SR, Greiner N, Conti S, Barra B, Zhuang K, Kaeser M, Ijspeert A, Capogrosso M. Spatiotemporal Maps of Proprioceptive Inputs to the Cervical Spinal Cord During Three- Dimensional Reaching and Grasping. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 2020. DOI: 10.1109/TNSRE.2020.2986491

Liew S-L, Zavaliangos‐Petropulu A, Jahanshad N, E Lang CE, Hayward KS, ... Wittenberg GF, Wong KA, Yu C, Cramer SC, Thompson PM. The ENIGMA Stroke Recovery Working Group: Big data neuroimaging to study brain–behavior relationships after stroke. Human Brain Mapping. 2020; 1-20. DOI: 10.1002/hbm.25015

Beringer C, Mansouri M, Fisher LE, Collinger JL, Munin MC, Boninger ML, Gaunt RA. The effect of wrist posture on extrinsic finger muscle activity during single joint movements. Scientific Reports. 2020. DOI: 10.1038/s41598-020-65167-x

Downey JE, Quick KM, Schwed N, Weiss JM, Wittenberg GF, Boninger ML, Collinger JL. The Motor Cortex Has Independent Representations for Ipsilateral and Contralateral Arm Movements But Correlated Representations for Grasping. Cerebral Cortex. 2020 Jun 4. bhaa120. PMID 32494819

Capogrosso M, Lempka SF. A computational outlook on neurostimulation. Bioelectronic Medicine. 2020 May 25; 6(10). DOI: 10.1186/s42234-020-00047-3

Jorge A, Royston DA, Tyler-Kabara EC, Boninger ML, Collinger JL. Classification of Individual Finger Movements Using Intracortical Recordings in Human Motor Cortex. Neurosurgery. 2020; nyaa026. PMID: 32140722.

Foldes ST, Boninger ML, Weber D, Collinger JL. Effects of MEG-based neurofeedback for hand rehabilitation after tetraplegia: preliminary findings in cortical modulations and grip strength. J. Neural Eng. 2020 Apr 9; 17(2):026019. PMID: 32135525

Weiss JM, Gaunt RA, Franklin R, Boninger ML, Collinger JL. Demonstration of a portable intracortical brain-computer interfaces. Brain-Computer Interfaces. 2020; 6(4): 106-117. DOI: 10.1080/2326263X.2019.1709260


Huggins JE, Guger C, Aarnoutse E, Allison B, Anderson CW, Bedrick S, Besio W, Chavarriaga R, Collinger JL, Do AH, Herff C, Hohmann M, Kinsella M, Lee K, Lotte F, Muller-Putz G, Nijholt A, Pels E, Peters B, Putze F, Rupp R, Schalk G, Scott S, Tangermann M, Tubig P, Zander T. Workshops of the seventh international brain-computer interface meeting: not getting lost in translation. Brain-Computer Interfaces. 2019; 1607163.

King KW, Cusack WF, Nanivadekar AC, Ayers CA, Urbin MA, Gaunt RA, Fisher LE, Weber D. DRG microstimulation evokes postural responses in awake, standing felines. J. Neural Eng. 2019; 17(1):016014. PMID: 31648208

Urbin MA, Liu M, Bottorff EC, Gaunt RA, Fisher LE, Weber DJ. Hindlimb motor responses evoked by microstimulation of the lumbar dorsal root ganglia during quiet standing. J. Neural Eng. 2019; 17(1):016019. PMID: 31597128

Nanivadekar A, Ayers CA, Gaunt RA, Weber D, Fisher LE. Selectivity of afferent microstimulation at the DRG using epineural and penetrating electrode arrays. J. Neural Eng. 2019; 17(1):016011. PMID: 31577993

Zheng X, Woeppel KM, Griffith AY, Chang E, Looker MJ, Fisher LE, Clapsaddle BJ, Cui XT. Soft conducting elastomer for peripheral nerve interface. Adv. Healthc. Mater. 2019; 8(9): e1801311. PMID: 30843365

Horn CC, Ardell JL, Fisher LE. Electroceutical targeting of the autonomic nervous system. Physiology. 2019; 34(2): 150-162. PMID: 30724129

Weiss JM,  Flesher SN, Franklin R, Collinger JL, Gaunt RA. Artifact-free recordings in human bidirectional brain-computer interfaces. J Neural Eng. 2019;16:016002. PMID: 30444217

Kashkoush AI, Gaunt RA, Fisher LE, Bruns TM, Weber DJ. Recording single- and multi-unit neuronal action potentials from the surface of the dorsal root ganglion. Sci. Rep. 2019; 9(1): 2786. PMID 30808921

Petersen BA, Nanivadekar AC, Chandrasekaran S, Fisher LE. Phantom limb pain: Neuromodulatory and neuroprosthetic approaches to treatment. Muscle Nerve. 2019; 59(2): 154-67. PMID: 30152101


Collinger JL, Gaunt RA, Schwartz AB. Progress towards restoring upper limb movement and sensation through intracortical brain-computer interfaces. Current Opinion in Biomedical Engineering, 2018; 8: 84-92. doi: 10.1016/j.cobme.2018.11.005

Downey JE, Schwed N, Chase SM, Schwartz AB, Collinger JL. Intracortical recording stability in human brain-computer interface users. J Neural Eng. 2018 Aug; 15(4): 046016 PMID: 29553484

Urbin MA, Royston DA, Weber DJ, Boninger ML, Collinger JL. What is the functional relevance of reorganization in primary motor cortex after spinal cord injury? Neurobiol Dis. 2018 Sep 12;121:286-295 PMID: 30217521

Huang WC, Ong XC, Kwon IS, Gopinath C, Fisher LE, Wu H, Fedder GK, Gaunt RA, Bettinger CJ. Ultracompliant hydrogel-based neural interfaces fabricated by aqueous-phase microtransfer printing. Adv. Func. Mat. 2018 May 24; 28(29). doi:10.1002/adfm.20181059

Downey JD, Weiss JM, Flesher SN, Thumser ZC, Marasco PD, Boninger ML, Gaunt RA, Collinger JL. Implicit Grasp Force Representation in Human Motor Cortical Recordings. Frontiers in Neuroscience. 2018; 14(4): 046016 PMID: 30429772

Degenhart AD, Hiremath SV, Yang Y, Foldes S, Collinger JL, Boninger M, Tyler-Kabara EC, Wang W. Remapping cortical modulation for electrocorticographic brain-computer interfaces: a somatotopy-based approach in individuals with upper-limb paralysis. J Neural Eng. 2018; 15(2): 026021. PMID: 29160240.


Downey JE, Brane L, Gaunt RA, Tyler-Kabara EC, Boninger ML, Collinger JL. Motor cortical activity changes during neuroprosthetic-controlled object interaction. Scientific Reports. 2017; 7: 16947. PMID: 29209023.

Foldes ST, Weber DJ, Collinger JL. Altered modulation of sensorimotor rhythms with chronic paralysis. J Neurophysiol. 2017; 118(4): 2412-2420. PMID: 28768745.

Yang Y, Dickey MW, Fiez J, Murphy B, Mitchell T, Collinger J, Tyler-Kabara E, Boninger M, Wang W. Sensorimotor experience and verb-category mapping in human sensory, motor, and parietal neurons. Cortex; 92: 304-319. PMID: 28575757.

Huggins JE, Guger C, Ziatc M, Zander TO, Taylor D, Tangermann M,Soria-Frisch A, Simeral J, Scherer R, Rupp R, Ruffini G, Robinson DKR, Ramsey NF, Nijholt A, Müller-Putz G, McFarland DJ, Mattia D, Lancer BJ, Kinderman P, Iturrate I, Herff C, Gupta D, Do AH, Collinger JL, Chavarriaga R, Chase SM, Bleichner MG, Batista A, Anderson CW and Aarnoutse EJ. Workshops of the Sixth International Brain-Computer Interface Meeting: brain-computer interfaces past, present, and future. Brain-Computer Interfaces; 4(1-2SI): 3-36. PMID: 29152523

Hiremath SV, Tyler-Kabara EC, Wheeler JJ, Moran DW, Gaunt RA, Collinger JL, Foldes ST, Weber DJ, Chen W, Boninger ML, Wang W. Human perception of electrical stimulation on the surface of the somatosensory cortex. PLoS ONE; 12(5): e0176020. PMID: 28489913.


Flesher SN, Collinger JL, Foldes ST, Weiss JM, Downey JE, Tyler-Kabara EC, Bensmaia SJ, Schwartz AB, Boninger ML, Gaunt RA. Intracortical microstimulation of human somatosensory cortex. Sci Transl Med; 8(361): 361ra141. PMID: 27738096.

Ayers CA, Fisher LE, Gaunt RA, Weber DJ. Microstimulation of the lumbar DRG recruits primary afferent neurons in localized regions of lower limb. J Neurophysiol; 116(1): 51-60. PMID: 27052583.

Downey JE, Weiss JM, Muelling K, Venkatraman A, Valois JS, Hebert M, Bagnell JA, Schwartz AB, Collinger JL. Blending of brain-machine interface and vision-guided autonomous robotics improves neuroprosthetic arm performance during grasping. J Neuroeng Rehabil; 13: 28. PMID: 26987662.

Zhang J, Li X, Foldes ST, Wang W, Collinger JL, Weber DJ, Bagic A. Decoding brain states based on magnetoencephelography from prespecified cortical regions. IEEE Trans Biomed Eng; 63(1): 30-42. PMID: 26699648.


Foldes S, Weber DJ, Collinger JL. Magnetoencephalography-based neurofeedback for hand rehabilitation. J Neuroeng Rehabil; 12: 85. PMID: 26392353.

Hiremath SV, Chen W, Wang W, Foldes S, Yang Y, Tyler-Kabara EC, Collinger JL, Boninger ML. Brain-computer interface learning for systems based on electrocorticography and intracortical microelectrode arrays. Frontiers Integrative Neurosci. 2015; 9(40): 1-10. PMID: 26113812.

Bruns TM, Weber DJ, Gaunt RA. Microstimulation of afferents in the sacral dorsal root ganglia can evoke reflex bladder activity. Neurol Urodyn; 34(1): 65-71. PMID: 24464833.

Kim S, Callier T, Tabot GA, Gaunt RA, Tenore FV, Bensmaia SJ. Behavioral assessment of sensitivity to intracortical microstimulation of primate somatosensory cortex. Proc Natl Acad Sci; 112(49): 15202-7. PMID: 26504211.

Rajan AT, Boback JL, Dammann JF, Tenore FV, Webster BA, Otto KJ, Gaunt RA, Bensmaia SJ. The effects of chronic intracortical microstimulation on neural tissue and fine motor behavior. J Neural Eng; 12(6): 066018. PMID: 26479701.

Kolarcik CL, Catt K, Rost E, Albrecht IN, Borbeau D, Du Z, Kozai TD, Luo X, Weber DJ, Cui XT. Evaluation of poly(3,4-ethylenedioxythiopene)/carbon nanotube neural electrode coatings for stimulation in the dorsal root ganglion. J Neural Eng; 12(1): 016008. PMID: 25485675.


Wodlinger B, Downey JE, Tyler-Kabara EC, Schwartz a B, Boninger ML, Collinger JL. Ten-dimensional anthropomorphic arm control in a human brain-machine interface: difficulties, solutions, and limitations. J Neural Eng; 2014 Dec 16;12(1):016011. PMID: 25514320.

Debnath S, Bauman MJ, Fisher LE, Weber DJ, Gaunt RA. Microelectrode array recordings from the ventral roots in chronically implanted cats. Front Neurol; 5:104. PMID: 25071697.

Collinger JL, Vinjamuri R, Degenhart AD, Weber DJ, Sudre GP, Boninger ML, Tyler-Kabara EC, Wang W. Motor-related brain activity during action observation: a neural substrate for electrocorticographic brain-computer interfaces after spinal cord injury. Front Integr Neurosci. 2014; 8(17):1-10. PMID: 24600359.

Fisher LE, Ayers CA, Ciollaro M, Ventura V, Weber DJ, Gaunt RA. Chronic recruitment of primary afferent neurons by microstimulation in the feline dorsal root ganglia. J Neural Eng; 11(3): 036007. PMID: 24762981.

Chen KH, Dammann JF, Boback JL, Tenore FV, Otto KJ, Gaunt RA, Bensmaia SJ. The effect of chronic intracortical microstimulation on the electrode-tissue interface. J Neural Eng; 11(2): 026004. PMID: 24503702.

Sicari BM, Rubin JP, Dearth CL, Wolf MT, Ambrosio F, Boninger M, Turner NJK, Weber DJ, Simpson TW, Wyse A, Brown EH, Dziki JL, Fisher LE, Brown S, Badylak SF. Sci Trans Med; 6(234): 234ra58. PMID: 24786326.

Kozai TD, Gugel Z, Li X, Gilgunn PJ, Khilwani R, Ozdoganlar OB, Fedder GK, Weber DJ, Cui XT. Chronic tissue response to carboxymethyl cellulose based dissolvable inertion needle for ultra-small neural probes. Biomaterials; 35(34): 9255-68. PMID: 25128375.

Collinger JL, Kryger M, Barbara R, Betler T, Bowsher K, Brown EHP, Clanton ST, Degenhart A, Foldes S, Gaunt RA, Gyulai FE, Harchick EA, Harrington D, Helder JB, Hemmes T, Johannes MS, Katyal KD, Ling GSF, McMorland AJC, Palko K, Para MP, Scheuermann J, Schwartz A, Skidmore ER, Solzbacher F, Srikameswaran AV, Swanson DP, Swetz S, Tyler-Kabara EC, Velliste M, Wang W, Weber DJ, Wodlinger B, Boninger M. Collaborative approach in the development of high performance brain-computer interfaces for a neuroprosthetic arm: translation from animal models to human control. Clinical Trans Sci. 2014; 7(1): 52-59. PMID: 24528900.


Collinger JL, Foldes S, Bruns TM, Wodlinger B, Gaunt R, Weber DJ. Neuroprosthetic technology for individuals with spinal cord injury. J Spinal Cord Med. 2013; 36(4): 258-72. PMID: 23820142.

Bruns TM, Wagenaar JB, Bauman MJ, Gaunt RA, Weber DJ. Real-time control of hind limb functional electrical stimulation using feedack from dorsal root ganglia recordings. J Neural Eng; 10(2): 026020. PMID: 23503062.

Collinger JL, Boninger ML, Bruns TM, Curley K, Wang W, Weber DJ. Functional priorities, assistive technology, and brain-computer interfaces after spinal cord injury. Journal of Rehabilitation Research and Development. 2013; 50(2):145. PMID: 23760996.

Collinger JL, Wodlinger B, Downey JE, Wang W, Tyler-Kabara EC, Weber DJ, et al. High-performance neuroprosthetic control by an individual with tetraplegia. Lancet. 2013; 381(9866): 557-64. PMID: 23253623.

Wang W, Collinger JL, Degenhart AD, Tyler-Kabara EC, Schwartz AB, Moran DW, et al. An electrocorticographic brain interface in an individual with tetraplegia. PloS one. 2013; 8(2): e55344. PMID: 23405137.

Unadkat JV, Bourbeau D, Afrooz PN, Solari MG, Washington KM, Pulikkottil BJ, Weber DJ, Lee WP. Functional outcomes following multiple acute rejections in experimental vascularized composite allotransplantation. Plast Reconstr Surg; 131(5): 720e-30e. PMID: 23629111.

Li Y, Smith LH, Hargrove LJ, Weber DJ, Loeb GE. Sparse optimal motor estimation (SOME) for extracting commands for prosthetic limbs. IEEE Trans Neural Syst Rehabil Eng; 21(1): 104-11. PMID: 23033331.


Kolarcik CL, Bourbeau D, Azemi E, Rost E, Zhang L, Lagenaur CF, Weber DJ, Cui XT. In vivo effects of L1 coating on inflammation and neuronal health at the electrode-tissue interface in rat spinal cord and dorsal root ganglion. Acta Biomater; 8(10): 3561-75. PMID: 22750248.

Turner NJ, Badylak JS, Weber DJ, Badylak SF. Biological scaffold remodeling in a dog model of complex musculoskeletal injury. J Surg Res; 176(2): 490-502. PMID: 22341350.

Weber DJ, Friesen R, Miller LE. Interfacing the somatosensory system to restore touch and proprioception: essential considerations. J Mot Behav; 44(6): 403-18. PMID: 23237464.


Vinjamuri R, Weber DJ, Mao Z-H, Collinger JL, Degenhart AD, Kelly JW, et al. Toward synergy-based brain-machine interfaces. IEEE Trans Inf Technol Biomed; 15(5): 726-36. PMID: 21708506.

Xu Y, Sudre GP, Wang W, Weber DJ, Kass RE. Characterizing global statistical significance of spatiotemporal hot spots in magnetoencephalography/ electroencephalography source space via excursion algorithms. Stat Med; 30(23): 2854-66. PMID: 21786281.

Bruns TM, Gaunt RA, Weber DJ. Multielectrode array recordings of bladder ad perineal primary afferent activity from the sacral dorsal root ganglia. J Neural Eng; 8(5): 056010. PMID: 21878706.

Collinger JL, Dicianno BE, Weber DJ, Cui XT, Wang W, Brienza DM, et al. Integrating rehabilitation engineering technology with biologics. PM R; 3(6 Suppl 1): S148-57. PMID: 21703573.

Degenhart AD, Kelly JW, Ashmore RC, Collinger JL, Tyler-Kabara EC, Weber DJ, et al. Craniux: a LabVIEW-based modular software framework for brain-machine interface research. Comput Intell Neurosci; 363565. PMID: 21687575.

Weber DJ, London BM, Hokanson JA, Ayers CA, Gaunt RA, Torres RR, Zaaimi B, Miller LE. Limb-state information encoded by peripheral and central somatosensory neurons: implications for an afferent interface. IEEE Trans Neural Syst Rehabil Eng; 19(5): 501-13. PMID: 21878419.

Kelly JW, Siewiorek DP, Smailagic A, Collinger JL, Weber DJ, Wang W. Fully automated reduction of ocular artifacts in high-dimensional neural data. IEEE Trans Biomed Eng; 58(3):5 98-606. PMID: 21097374.

Borbeau DJ, Hokanson JA, Rubin JE, Weber DJ. A computational model for estimating recruitment of primary afferent fibers by intraneural stimulation in the dorsal root ganglia. J Neural Eng; 8(5): 056009. PMID: 21844639.

Zhang J, Sudre G, Li X, Wang W, Weber DJ, Bagic A. Clustering linear discriminant analysis for MEG-based brain computer interfaces. IEEE Trans Neural Syst Rehabil Eng; 19(3): 221-31. PMID: 21342856.

Wagenaar JB, Ventura V, Weber DJ. State-space decoding of primary afferent neuron firing rates. J Neural Eng; 8(1): 016002. PMID: 21245525.

Sudre G, Parkonnen L, Bock E, Baillet S, Wang W, Weber DJ. rtMEG: a real-time software interface for magnetoencephalography. Comput Intell Neurosci; 327953. PMID: 21687573.


Wang W, Sudre GP, Xu Y, Kass RE, Collinger JL, Degenhart AD, et al. Decoding and cortical source localization for intended movement direction with MEG. J Neurophysiol; 104(5): 2451-61. PMID: 20739599.

Guo C, Li X, Taulu S, Wang W, Weber DJ. Real-time robust signal space separation for magnetoencephalography. IEEE Trans Biomed Eng; 57(8): 1856-66. PMID: 20176529.

Wang W, Collinger JL, Perez MA, Tyler-Kabara EC, Cohen LG, Birbaumer N, et al. Neural interface technology for rehabilitation: exploiting and promoting neuroplasticity. Phys Med Rehabil Clin N Am; 21(1): 157-78. PMID: 19951784.

Henzel MK, Munin MC, Niyonkuru C, Skidmore ER, Weber DJ, Zafonte RD. Comparison of surface and ultrasound localization to identify forearm flexor muscles for boltulinum toxin injections. PM R; 2(7): 642-6. PMID: 20659720.

Brose SW, Weber DJ, Salatin BA, Grindle GG, Wang H, Vazquez JJ, Cooper RA. The role of assistive robotics in the lives of persons with disability. Am J Phys Med Rehabil; 89(6): 509-21. PMID: 20134305.

Weber DJ, Skidmore ER, Niyonkuru C, Chang CL, Huber LM, Munin MC. Cyclic functional electrical stimulation does not enhance gains in hand grasp function when used as an adjunct to onabotulinumtoxinA and task practice therapy: a single-blinded randomized controlled pilot study. Arch Phys Med Rehabil; 91(5): 679-86. PMID: 20434603.


Gaunt RA, Hokanson JA, Weber DJ. Microstimulation of primary afferent neurons in the L7 dorsal root ganglia using multielectrode arrays in anesthetized cats: thresholds and recruitment properties. J Neural Eng; 6(5): 055009. PMID: 19721181.

Chang CL, Munin MC, Skidmore ER, Niyonkuru C, Huber LM, Weber DJ. Effect of baseline spastic hemiparesis on recovery of upper-limb function following botulinum toxin type A injections and postinjection therapy. Arch Phys Med Rehabil; 90(9): 1462-8. PMID: 19735772.